Quinolines and derivatives
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Filtered Search Results
Chemscene ChemScene | 2-Aminoquinoline | 5G | CS-W007524 | 0.98 | 580-22-3| MFCD00038079 | 144.18
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ChemScene | 2-Aminoquinoline | 5G | CS-W007524 | 0.98 | 580-22-3| MFCD00038079 | 144.18
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AdipoGen Dihydroethidium
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Chemical. CAS 104821-25-2. Formula C21H21N3. MW 315.41. Synthetic. Redox indicator. Blue fluorescence until oxidized to ethidium. Can be used for detecting superoxide radical in cells, tissues and organisms.
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AdipoGen Dihydroethidium
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Chemical. CAS 104821-25-2. Formula C21H21N3. MW 315.41. Synthetic. Redox indicator. Blue fluorescence until oxidized to ethidium. Can be used for detecting superoxide radical in cells, tissues and organisms.
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Selleck Chemical LLC Dihydroethidium
Dihydroethidium (DHE HE Hydroethidine PD-MY 003) is a cell-permeable blue fluorogenic probe used for detecting intracellular superoxide radical anion
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Alkali Scientific ALKALI SCIENTIFIC INC
5000659621 ETHIDIUM BROMIDE DNA STAIN
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Medchemexpress LLC 5-Amino-8-hydroxyquinoline | 13207-66-4 | 160.18 | 250 MG
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5-Amino-8-hydroxyquinoline is an orally active, non-competitive 20S proteasome inhibitor. It inhibits NF-κB activity and induces cancer cell death, while exhibiting low cytotoxicity towards normal hematopoietic cells. This compound is suitable for cancer research, particularly in the study of leukemia.
- Orally active non-competitive 20S proteasome inhibitor
- Inhibits NF-κB activity
- Induces cancer cell death
- Low cytotoxicity towards normal hematopoietic cells
- Suitable for cancer research, including leukemia
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Apexbio Technology LLC Resiquimod (R-848) 144875-48-9 100mg
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Resiquimod (R-848) is an immunomodulatory small molecule structurally related to imiquimod It functions primarily by activating immune responses via inducing cytokine release In vitro studies with human peripheral blood mononuclear cells (PBMC) indicate that Resiquimod promotes dose-dependent production of cytokines including interferon-alpha (IFN- ) tumor necrosis factor (TNF) interleukin-1 (IL-1 ) and interleukin-6 (IL-6) Mechanistically Resiquimod increases intracellular IL-1 levels and both monocytes and B-cells respond by secreting IFN upon stimulation In addition it elevates mRNA expression of IFN- TNF and IL-8 in treated PBMC relative to untreated controls Resiquimod demonstrates antiviral and antitumor activities in preclinical animal models frequently utilized as an immune response potentiator and Toll-like receptor (TLR) agonist in biomedical investigations (IC50 values typically range in low micromolar)
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Apexbio Technology LLC Sivelestat (ONO-5046) 127373-66-4 200mg
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Sivelestat (ONO-5046) is a selective inhibitor of neutrophil elastase with an IC50 value of 44 nM Neutrophil elastase a serine protease secreted by activated neutrophils can degrade extracellular matrix components and contribute to tissue injury in inflammatory diseases such as rheumatoid arthritis emphysema acute respiratory distress syndrome (ARDS) and septic shock Sivelestat inhibits human neutrophil elastase in a competitive manner and similarly reduces the activity of leukocyte elastases from rodents In animal sepsis models sivelestat attenuates renal dysfunction reduces inflammatory markers like NGAL and increases survival rates Clinically this compound is utilized for managing acute lung injury associated with systemic inflammatory response syndrome and ARDS
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SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES 1G DEFEROXAMINE MESYLATE
NC2943806 1G DEFEROXAMINE MESYLATE
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eMolecules 4-HYDROXYCYCLOHEXAN-1-ONE 10G
5000224201 4-HYDROXYCYCLOHEXAN-1-ONE 10G
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eMolecules BISPERFLUOROPHENYL CARBO 10G
5000224245 BISPERFLUOROPHENYL CARBO 10G
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eMolecules 4-4 6-DIMETHOXY-1 3 5-TR 100G
5000225212 4-4 6-DIMETHOXY-1 3 5-TR 100G
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Medchemexpress LLC RU.521 100mg | 2262452-06-0 | 100 MG
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RU.521 is a small-molecule inhibitor of cyclic GMP-AMP synthase (cGAS) used in research to suppress cGAS-mediated interferon signaling. It is supplied as a high-purity solid and is provided in multiple sizes and formulations for in vitro and cellular studies.
- High purity (99.95%) for reproducible results.
- Potent, selective inhibition of cGAS in cellular assays.
- Available in multiple sizes and DMSO solution formats for flexibility.
- Stable as a powder at -20°C for long-term storage.
- Molecular weight 415.23; formula C19H12Cl2N4O3.
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Medchemexpress LLC Pyrimido[4,5-d]pyrimidinone derivative (1-cyclobutyl, 2,6-dimethylphenyl, 2-methoxy-4-piperazinyl) | 2172617-15-9 | 99.8% | 100 MG
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YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor for research use. It displays low-nanomolar activity against SIK isoforms and is supplied as a purified small-molecule reagent.
- Potent SIK inhibition (SIK1 = 6.56 nM, SIK2 = 1.77 nM, SIK3 = 20.5 nM).
- High reported purity (approximately 99.8% by HPLC).
- Molecular formula C30H37N7O2; molecular weight 527.66 g/mol.
- Available in multiple sizes and formats, including milligram quantities and a 10 mM solution in DMSO.
- For research use only; not for human or veterinary applications.
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Medchemexpress LLC Cytochrome c (bovine heart) | 9007-43-6 | MFCD00130890 | 95.0% | 12,327 Da | 200MG
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Cytochrome c (bovine heart) is a heme-containing mitochondrial protein provided as a lyophilized powder for research use. It functions in electron transport and is commonly used as a reagent or standard in biochemical assays of oxidative phosphorylation, electron-transfer reactions, and apoptosis research. The material is characterized by its protein sequence and heme prosthetic group and is supplied at ~95% purity.
- Heme-containing mitochondrial protein suitable for biochemical studies.
- Commonly used as a reagent or standard in electron transport and apoptosis assays.
- Provided as a lyophilized powder for convenient storage and handling.
- Purity approximately 95.0% as listed by the manufacturer.
- Available in multiple pack sizes, including a 200 mg pack.
- Identified by CAS number 9007-43-6 for reference and traceability.
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